A polygenic score is a statistical value calculated using many genetic variants. At MyGenetics, we use thousands — and in some cases millions — of variants to estimate how you compare to the general population for a given trait or condition.

For example, if your polygenic score places you in the 95th percentile for height, that means you’re genetically predicted to be taller than about 95% of people. In a group of 20 individuals, you would expect to be taller than roughly 19 of them, though environment also plays an important role in actual height.

We test over 20 traits and conditions.

A single nucleotide polymorphism (SNP) is a genetic variant found in at least 1% of humans. It occurs when a single DNA base differs between individuals.

For example, imagine you have C:C (homozygous cytosine) on chromosome 11 at position 66,560,624. This location is within the ACTN3 gene, which influences fast-twitch muscle fiber function. The C allele is associated with functional ACTN3 protein production, so individuals with the C:C genotype typically have a genetic predisposition toward greater muscular power and strength compared to those with the nonfunctional T allele.

We test over 100 different SNPs per report.

At MyGenetics, we analyze your genome and compare it to a wide range of modern human populations. We identify which populations your genetic profile most closely resembles and break these similarities down by percentage.

We have over 50 different ethnic group reference populations. 

Our company follows strict confidentiality standards to ensure your genetic data is fully protected. Employees do not have access to your raw genetic information, and we never sell or share your data with any third parties. Your genome remains securely stored and used only for the services you choose.